"Paleoproterozoic Perils" is the third episode of Joe & Mac.
"Welcome.. to.. the.. right, left, right, left." - Jon
- Jon begins singing bits from the musical "Rent", and they begin discussing it. They talk about the differences between the broadway cast and the movie cast. Jon expresses a high regard towards Anthony Rapp, who plays Mark Cohen in Rent.
- Jon and Arin make a few Jonathan Blow jokes.
- Arin tries to talk about Jane McGonigal, but Jon cuts him off repeatedly, making a joke about Professor McGonagall from the Harry Potter series. Arin resumes his thoughts in Finale (Joe & Mac).
- At 0:16, Jon sings "Up down, up down, left right, left right, B A Start". This is "Noise Channel Rocker" by Kitsune². He sings the same bit again in Sunken in the Snow at 3:22.
- At 0:57, Jon and Arin sing "Goodbye Love" and "I'll Cover You (Reprise)" from the musical Rent. They also sing "Goodbye Love" in Slicing and Dicing and New York State of Lava.
- At 3:11, Jon sings the song "Epiphany" from Sweeney Todd.
- At 8:50, Jon sings the theme song to Goof Troop.
- At 11:50, Jon sings "No Good Deed" from the musical Wicked.
- This episode contains the samples for JerryTerry's "Joe & Mac" remix.
"She's got a lot of interesting things to say, but I think she's a--" - Arin
"Dobby's a elf." - Jon
"Shut up!" - Arin