Are Jon and Arin Still Friends? is a popular meme in the Grumps fan community, which was mostly prevalent for the first two years after Jon left the show. "Jon" and "Arin" are usually replaced by some other combination of names or concepts, e.g. "Are Barry and Suzy still friends?" or "Are Danny and Skittles still friends?"
Jon's departure from the show was unprecedented and abrupt from the viewers' perspective, as there had been no lead-up to him leaving the show before the posting of Ode to Jon, where his departure was announced. While Jon had offered plenty of reasons for leaving Game Grumps (such as wanting to focus more on his own series instead of a Let's Play, and moving across the country to New York), fans still speculated on the circumstances that led to his departure.
After Jon left the show, Arin and Danny very rarely mentioned Jon's involvement on the show at all for a year afterward, as Jon had requested to not be associated with Game Grumps while he was focusing on his own show. In addition, the lack of interaction between Jon and Arin on the internet despite the fact that they share several social circles led to lovelies asking earnestly if there is bad blood between the former partners. Some viewers would then fan the flames by circulating rumors of altercations that might have led to a falling out between the two. Others (for whom the question was getting tiresome) began substituting other names as a joke, and a meme was born.
Recently more and more evidence of Jon and Arin hanging out together has surfaced, showing that there is no bad blood between them, or that they have made up in case there ever was. These include photos taken at MAGfest 13, as well as Ross confirming that they are still friends on a Reddit AMA. The uncertainty between their friendship was a pivotal point of Jon's Starcade series, where Arin and Jon were re-united as friends in the final episode. Jon would later mention in a Q&A that he regretted the way he handled his departure from Game Grumps, and that the Starcade finale was intended to lay those rumors to rest. Arin has also flouted the possibility of collaborating with Jon on the channel in the future, and is especially tired of people speculating on the two of them having some kind of falling out based on vague and unconfirmed statements. He and Danny have also spoken more openly about Jon's involvement in the show since then.